Yoichi Kurebayashi Selected Research

N- (2- hydroxyethyl)- N,2- dimethyl- 8- ((5- methyl- 3,4- dihydro- 2H- chromen- 4- yl)amino)imidazo(1,2- a)pyridine- 6- carboxamide

2/2009

N-(2-hydroxyethyl)-N,2-dimethyl-8-{[(4R)-5-methyl-3,4-dihydro-2H-chromen-4-yl]amino}imidazo[1,2-a]pyridine-6-carboxamide (PF-03716556), a novel, potent, and selective acid pump antagonist for the treatment of gastroesophageal reflux disease.

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Yoichi Kurebayashi Research Topics

Disease

5	Hypersensitivity (Allergy) 09/2010 - 12/2007
3	Inflammation (Inflammations) 09/2016 - 02/2008
3	Hyperalgesia 07/2009 - 04/2009
2	Rheumatoid Arthritis 05/2017 - 07/2016
1	Psoriasis (Pustulosis Palmaris et Plantaris) 09/2016
1	Respiratory Hypersensitivity 07/2016
1	Lung Diseases (Lung Disease) 07/2016
1	Dermatitis 07/2016
1	Arthritis (Polyarthritis) 07/2016
1	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 09/2010
1	Neuralgia (Stump Neuralgia) 07/2009
1	Visceral Pain 04/2009
1	Gastroesophageal Reflux (GERD) 02/2009
1	Necrosis 02/2008
1	Pain (Aches) 01/2008
1	Abdominal Pain (Pain, Abdominal) 01/2008

Drug/Important Bio-Agent (IBA)

3	Morphine (MS Contin)FDA LinkGeneric 04/2009 - 01/2008
3	sym-trinitrobenzeneIBA 01/2008 - 12/2007
3	Sulfonic AcidsIBA 01/2008 - 12/2007
2	LigandsIBA 09/2010 - 01/2008
2	Pregabalin (Lyrica)FDA Link 09/2010 - 07/2009
2	Gabapentin (Neurontin)FDA LinkGeneric 04/2009 - 04/2009
1	tofacitinibIBA 05/2017
1	Janus Kinase InhibitorsIBA 05/2017
1	Messenger RNA (mRNA)IBA 09/2016
1	SteroidsIBA 09/2016
1	Imiquimod (Aldara)FDA LinkGeneric 09/2016
1	Interleukin-22 (IL-22)IBA 09/2016
1	Betamethasone (Celestone)FDA Link 09/2016
1	CytokinesIBA 09/2016
1	InterferonsIBA 09/2016
1	InterleukinsIBA 09/2016
1	Ointments (Pastes)IBA 09/2016
1	OxazoloneIBA 07/2016
1	Integrin alpha1beta1IBA 07/2016
1	SmokeIBA 07/2016
1	Collagen Type II (Type II Collagen)IBA 07/2016
1	Calcium Channels (Calcium Channel)IBA 09/2010
1	Mexiletine (Mexitil)FDA LinkGeneric 07/2009
1	Histamine (Histamine Dihydrochloride)FDA Link 02/2009
1	pyridineIBA 02/2009
1	N- (2- hydroxyethyl)- N,2- dimethyl- 8- ((5- methyl- 3,4- dihydro- 2H- chromen- 4- yl)amino)imidazo(1,2- a)pyridine- 6- carboxamideIBA 02/2009
1	AcidsIBA 02/2009
1	Proton Pump InhibitorsIBA 02/2009
1	Peroxidase (Myeloperoxidase)IBA 02/2008
1	salicylhydroxamic acid (SHAM)IBA 01/2008
1	Analgesics (Analgesic Drugs)IBA 01/2008
1	1 alpha,3 alpha,5 alpha- 3- aminomethyl- bicyclo(3.2.0)heptane- 3- acetic acidIBA 01/2008
1	doxantrazoleIBA 12/2007
1	Mast Cell StabilizersIBA 12/2007

Therapy/Procedure

3	Therapeutics 09/2016 - 02/2009
2	Laparotomy 01/2008 - 12/2007